Towards environmentally friendly production of active pharmaceutical ingredients with a flow reactor

07-08-2017

Towards environmentally friendly production of active pharmaceutical ingredients with a flow reactor
Chemists at Bielefeld University working on new production methods

Mostly, the chemical industry still follows very extensive procedures when producing active pharmaceutical ingredients and other complex substances. Often, each intermediate has to be produced in a separate fashion within large reactor vessels. Chemists at Bielefeld University are working on an alternative together with international project partners: the flow method. This combines the production stages and proceeds in microreactors in which the desired substance can be produced without intermediate isolations. The European Union’s research programme is funding the project ‘ONE-FLOW’ with a total of four million Euros. Bielefeld University has now succeeded in gaining a scientist from the renowned Keio University (Japan) for the project. Dr. Yasunobu Yamashita will be starting his work on the project next Tuesday at the beginning of August 2017

Professor Dr. Harald Gröger from the Center for Biotechnology (CeBiTec) and Chair of Organic Chemistry I of Bielefeld University is the head of the German ONE-FLOW sub-project. The Bielefeld scientist is active in the field of ‘green chemistry’ aiming to develop environmentally friendly chemical reactions. Eindhoven University of Technology (Netherlands) is coordinating the entire ONE-FLOW project with eight partners. Gröger’s research team is working particularly closely with Professor Dr. Volker Hessel’s team from Eindhoven. Hessel is the project coordinator and an expert on micro-reaction technology and flow chemistry.

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